- Dan Plews and Ed Maunder 

As we have mentioned in previous blogs, during ultra-endurance events lasting ~8-15 hours like long-distance triathlon, the preservation of endogenous carbohydrate (CHO) stores is one of the key determinants of success (25). As humans, we possess a finite capacity to store CHO energy as glycogen, typically <3000 kcal, of which ~80% is stored in muscle and ~10-15% in the liver (7). Assuming typical running economy values observed in highly-trained distance runners (1.07 kcal.kg^-1.km^-1) (6) and a body mass of 68 kg, these endogenous CHO stores would not be sufficient to support even one marathon alone (~3070 kcal), let alone a marathon following a 3.8-km swim and a 180-km bike ride. Accordingly, exercise of sufficient duration and intensity – such as an Ironman – will deplete these endogenous CHO energy stores to very low concentrations, and this glycogen depletion has been linked to the fatigue we feel in the late stages...